Mycobacteriosis and Tuberculosis: Laboratory Diagnosis

Diagnosis of Tuberculosis: Novel Laboratory Methods

Despite advances in medical sciences in recent years, tuberculosis remains a worldwide health problem. Although there are many laboratory methods to accelerate the diagnosis, a delay in the definitive diagnosis of the disease is still a major clinical problem. Due to the slow growth of the causative agent, (Mycobacterium tuberculosis), isolation, identification, and other clinically important m...

Mycobacteriosis (tuberculosis) of Fishes

Modern laboratory diagnosis of tuberculosis.

One-third of the global population is believed to be infected with bacteria of the Mycobacterium tuberculosis complex, the causative agent of tuberculosis. More than 8 million new cases of tuberculosis occur annually leading to 2 million deaths. Mortality is particularly high in those coinfected with HIV and where the bacteria are multiple-drug-resistant strains--ie, strains resistant to at lea...

Pathogenesis of tuberculosis and other mycobacteriosis.

The evolution between Mycobacterium tuberculosis infection and active tuberculosis is multifactorial and involves different biological scales. The synthesis of ESAT-6 or the induction of alveolar macrophage necrosis are key, but to understand it, it is necessary to consider the dynamics of endogenous and exogenous reinfection, drainage of lung parenchyma and respiratory mechanics, local fibrosi...

Laboratory Diagnosis of Tuberculosis - Latest Diagnostic Tools

Microscopy has been a diagnostic tool for TB for over a century, and still currently the most rapid diagnostic method. Standard light microscopy (LM) and fluorescent microscopy (FM) are common methods. The recent development of light emitting diodes (LED), with the ap‐ propriate fluorescent light output for FM and low power consumption, has led to the devel‐ opment of simple, robust LED FM micr...